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An antigen as a substance that can mobilize the immune system and provoke an immune responses. Antigens are the target of all immune responses and are therefore regarded as intruders (Marieb & Hoehn, 2007).  Immunogenicity is the ability of a substance such as an antigen to stimulate the production of specific lymphocytes and antibodies(Marieb & Hoehn, 2007).  Vaccines have have a high potential to eradicate and alleviate the burden of disease in humans.  In order to design an effective vaccine for a specific disease or illness, a thorough understanding of how the immune system works and how different factors will increase or decrease immunogenicity, needs to be understood. This will ensure a higher efficacy of the vaccine.  We intend to provide you with an understanding of the science of how vaccines interact with our immune system. 


 * ** Immune System  **
 * ** ** ** Factors that effect immunogenicity  ** ** **
 * ** Receptors **
 * ** Dentritic Cells **
 * ** ** Toll-like receptors  ** **

** References **